Highlights and News

Disease activity and treatment response in early rheumatoid arthritis: an exploratory metabolomic profiling in the NORD-STAR cohort - Arthritis Research & Therapy

Disease activity and treatment response in early rheumatoid arthritis: an exploratory metabolomic profiling in the NORD-STAR cohort  Arthritis Research & Therapy

Deep molecular profiling of synovial biopsies in the STRAP trial identifies signatures predictive of treatment response to biologic therapies in rheumatoid arthritis - Nature

Deep molecular profiling of synovial biopsies in the STRAP trial identifies signatures predictive of treatment response to biologic therapies in rheumatoid arthritis  Nature

Stratification of biological therapies by pathobiology in biologic-naive patients with rheumatoid arthritis (STRAP and STRAP-EU): two parallel, open-label, biopsy-driven, randomised trials - The Lancet

Stratification of biological therapies by pathobiology in biologic-naive patients with rheumatoid arthritis (STRAP and STRAP-EU): two parallel, open-label, biopsy-driven, randomised trials  The Lancet

Deciphering the molecular landscape of rheumatoid arthritis offers new insights into the stratified treatment for the condition - Frontiers

Deciphering the molecular landscape of rheumatoid arthritis offers new insights into the stratified treatment for the condition  Frontiers

Computational approaches in rheumatic diseases - Deciphering complex spatio-temporal cell interactions - ScienceDirect.com

Computational approaches in rheumatic diseases - Deciphering complex spatio-temporal cell interactions  ScienceDirect.com

TOFA-PREDICT study protocol: a stratification trial to determine key immunological factors predicting tofacitinib efficacy and drug-free remission in psoriatic arthritis (PsA) - BMJ Open

TOFA-PREDICT study protocol: a stratification trial to determine key immunological factors predicting tofacitinib efficacy and drug-free remission in psoriatic arthritis (PsA)  BMJ Open

Is There a Missing Link in Rheumatoid Arthritis Management? - European Medical Journal

Is There a Missing Link in Rheumatoid Arthritis Management?  European Medical Journal

Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial - Nature

Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial  Nature

Towards stratified treatment of JIA: machine learning identifies subtypes in response to methotrexate from four UK cohorts - The Lancet

Towards stratified treatment of JIA: machine learning identifies subtypes in response to methotrexate from four UK cohorts  The Lancet

Clinical implications of synovial tissue phenotypes in rheumatoid arthritis - Frontiers

Clinical implications of synovial tissue phenotypes in rheumatoid arthritis  Frontiers

Location and amount of joint involvement differentiates rheumatoid arthritis into different clinical subsets - Nature

Location and amount of joint involvement differentiates rheumatoid arthritis into different clinical subsets  Nature

Precision medicine in psoriatic arthritis: how should we select targeted therapies? - The Lancet

Precision medicine in psoriatic arthritis: how should we select targeted therapies?  The Lancet

Synovial Tissue Heterogeneity in Rheumatoid Arthritis and Changes With Biologic and Targeted Synthetic Therapies to Inform Stratified Therapy - Frontiers

Synovial Tissue Heterogeneity in Rheumatoid Arthritis and Changes With Biologic and Targeted Synthetic Therapies to Inform Stratified Therapy  Frontiers

A longitudinal cohort study uncovers plasma protein biomarkers predating clinical onset and treatment response of rheumatoid arthritis - Nature

A longitudinal cohort study uncovers plasma protein biomarkers predating clinical onset and treatment response of rheumatoid arthritis  Nature

A Pauci-Immune Synovial Pathotype Predicts Inadequate Response to TNFα-Blockade in Rheumatoid Arthritis Patients - Frontiers

A Pauci-Immune Synovial Pathotype Predicts Inadequate Response to TNFα-Blockade in Rheumatoid Arthritis Patients  Frontiers

Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes - Nature

Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes  Nature

Addition of Fibroblast-Stromal Cell Markers to Immune Synovium Pathotypes Better Predicts Radiographic Progression at 1 Year in Active Rheumatoid Arthritis - Frontiers

Addition of Fibroblast-Stromal Cell Markers to Immune Synovium Pathotypes Better Predicts Radiographic Progression at 1 Year in Active Rheumatoid Arthritis  Frontiers

Automated multi-scale computational pathotyping (AMSCP) of inflamed synovial tissue - Nature

Automated multi-scale computational pathotyping (AMSCP) of inflamed synovial tissue  Nature

Utility of Baseline Transcriptomic Analysis of Rheumatoid Arthritis Synovium as an Indicator for Long-Term Clinical Outcomes - Frontiers

Utility of Baseline Transcriptomic Analysis of Rheumatoid Arthritis Synovium as an Indicator for Long-Term Clinical Outcomes  Frontiers

Systems-biology analysis of rheumatoid arthritis fibroblast-like synoviocytes implicates cell line-specific transcription factor function - Nature

Systems-biology analysis of rheumatoid arthritis fibroblast-like synoviocytes implicates cell line-specific transcription factor function  Nature

Prediction of response of methotrexate in patients with rheumatoid arthritis using serum lipidomics - Nature

Prediction of response of methotrexate in patients with rheumatoid arthritis using serum lipidomics  Nature

Identification of biomarkers to stratify response to B-cell-targeted therapies in systemic lupus erythematosus: an exploratory analysis of a randomised controlled trial - The Lancet

Identification of biomarkers to stratify response to B-cell-targeted therapies in systemic lupus erythematosus: an exploratory analysis of a randomised controlled trial  The Lancet

Persistence of Mast Cell-Positive Synovitis in Early Rheumatoid Arthritis Following Treatment With Conventional Synthetic Disease Modifying Anti-Rheumatic Drugs - Frontiers

Persistence of Mast Cell-Positive Synovitis in Early Rheumatoid Arthritis Following Treatment With Conventional Synthetic Disease Modifying Anti-Rheumatic Drugs  Frontiers

Clinical Applications of Synovial Biopsy - Frontiers

Clinical Applications of Synovial Biopsy  Frontiers